منابع مشابه
Stem Cell Organoid Engineering
Organoid systems leverage the self-organizing properties of stem cells to create diverse multicellular tissue proxies. Most organoid models only represent single or partial components of a tissue, and it is often difficult to control the cell type, organization, and cell-cell/cell-matrix interactions within these systems. Herein, we discuss basic approaches to generate stem cell-based organoids...
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Recent technical advances in the stem cell field have enabled the in vitro generation of complex structures resembling whole organs termed organoids. Most of these approaches employ three-dimensional (3D) culture systems that allow stem cell-derived or tissue progenitor cells to self-organize into 3D structures. These systems evolved, methodologically and conceptually, from classical reaggregat...
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Recently emerging methodology for generating human tissues in vitro has the potential to revolutionize drug discovery and disease research. Currently, three-dimensional cell culture models either rely on the pronounced ability of mammalian cells to self organize in vitro 1-6 , or use bioengineered constructs to arrange cells in an organ-like configuration 7,8. While self-organizing organoids ca...
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The effects of the removal of 18-MEA on the dynamic contact angle (advancing contact angle and receding contact angle) and friction force (friction force microscopy (FFM)) were examined in the present study. Chemically untreated hair tresses formed more finely ordered bundles, with the fibers aligned more parallel to each other, in the wet state, and lying flat and aligned parallel to each othe...
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Copulas are a general tool for assessing the dependence structure of random variables. Important properties as well as a number of examples are discussed, including Archimedean copulas and the Marshall-Olkin copula. As measures of the dependence we consider linear correlation, rank correlation, the coefficients of tail dependence and association. Copulas are a tool for modeling and capturing th...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2021
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.94.0_3-o-b2-5